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1.
Neumologia y Cirugia de Torax(Mexico) ; 81(1):6-12, 2022.
Article in Spanish | EMBASE | ID: covidwho-1918351

ABSTRACT

Introduction: The pandemic of SARS-CoV-2 (COVID-19) has caused high rates of morbidity and mortality. The use of adequate diagnostic methods to identify the evolution of this disease is necessary;computerized tomography (CT) is of the main tools by image, with sensitivity of 96-99%. Different studies have created scales to evaluate the extent and severity of lung disease from COVID-19, with a variability in the results. Objective: To evaluate the use of a tomographic scale (TS) to determine the severity of lung affectation in COVID-19. Material and methods: Analytical cross-sectional study including patients with confirmed diagnosis of COVID-19 and initial CT. ATS was used to evaluate the lung affectation, to identify pulmonary pattern and to establish the state of the disease. Statistical analysis consisted in descriptive and analytical statistics (ROC curve). Results: 151 patients, mean age 50 years. The predominant pulmonary pattern was «crazy paving» (46%), identified in the phase of progression. The area under the ROC curve was 0.831 (95% CI: 0.764-0.898), with a cut-off value of 16.5 to discriminate the severe from non-severe affectation, with sensitivity 84% and specificity 74%. Conclusion: The use of TS in initial CT showed an acceptable sensitivity to identify the severity of the disease.

2.
Brazilian Journal of Infectious Diseases ; 26, 2022.
Article in Portuguese | EMBASE | ID: covidwho-1693864

ABSTRACT

Introdução: Na tuberculose pulmonar (TBp), os principais padrões radiológicos são cavitação e nódulos centrolobulares com padrão de árvore em brotamento, predominantemente nos lobos superiores, e espessamento das paredes brônquicas. No entanto, podemos encontrar manifestações radiológicas atípicas como os tuberculomas pulmonares, tornando o diagnóstico, nestes casos, mais desafiador. Geralmente, o tuberculoma pulmonar aparece isolado e ocorre em cerca de 5% dos casos de tuberculose pulmonar. Nódulos múltiplos, que mimetizam neoplasia pulmonar ou metástases, por sua vez, são ainda mais incomuns. Descrição do caso: Trata-se de uma paciente do sexo feminino, 43 anos, hipertensa, asmática e com diagnóstico de espondiloartrite com início do quadro, do qual não soube precisar data, caracterizado por tosse seca diária e eventualmente com secreção branca ou hemoptise, que piora à noite e melhora parcialmente com anti-histamínico. Há cerca de 1 ano e meio, apresentou dor em dorso e precórdio, que piorava ao esforço físico e tosse, sem fatores de melhora. Há 10 meses, apresentou dispneia aos pequenos esforços, quando teve diagnóstico de COVID-19, porém os sintomas pulmonares se exacerbaram progressivamente. Relata também sudorese noturna e perda ponderal de 7 kg em 3 meses. Em março de 2021, realizou PET CT que evidenciou nódulos pulmonares múltiplos em lobos inferiores e superior direito, sem atividade metabólica específica e de etiologia a esclarecer. Foi realizada segmentectomia pulmonar à direita, no entanto a análise histopatológica da peça revelou processo inflamatório crônico e extensas áreas de necrose caseosa em segmento de lobo inferior direito, sugerindo diagnóstico de TBp, sendo encaminhada para nosso serviço especializado. Foi descartado o HIV. Após 4 meses de uso de rifampicina, isoniazida, pirazinamida e etambutol, 4 comprimidos por dia, paciente refere melhora da tosse seca e da sudorese noturna, além de melhora da adinamia e astenia. Comentários: Geralmente, nódulos pulmonares múltiplos são malignos, chegando a responder a 80% dos casos. No entanto, tuberculose pulmonar no Brasil e na região nordeste, deve sempre ser considerada como diagnóstico diferencial, mesmo diante de imagem não típica.

3.
Neumologia y Cirugia de Torax(Mexico) ; 79(2):71-77, 2020.
Article in Spanish | EMBASE | ID: covidwho-1273814

ABSTRACT

Introduction: The SARS-CoV-2 pandemic is a major public health problem worldwide, with high morbidity and mortality rates. Computed tomography (CT) is essential in the diagnostic process given its high sensitivity. Objective: To describe the tomographic findings in COVID-19 lung involvement. Material and methods: Analytical crosssectional study. Patients attended at the INER, CDMX, with a current operational definition of a suspected case for COVID-19, who had a specific RT-PCR test and chest CT in the initial evaluation. A descriptive and analytical analysis was performed using the Student’s χ2 and t tests. The Epi-Info version 7 program was used. Results: 56 patients were analyzed, with an average age of 51 years, 61% were male. 52% presented comorbidities, with diabetes mellitus being the most frequent. The symptoms that were mostly observed were fever, cough and headache. The tomographic pattern that predominated was mixed, with a subpleural and bilateral location. Conclusion: The pulmonary tomographic spectrum of the studied population was characterized by two main patterns: Mixed type (areas of ground glass consolidation) and crazy paving.

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